[GeorgeTH]

I keep 2 mirrors on 2 harddrives (on 2 network computers) of everything in exactly the order it's on the servers (as long as it's on the server it's on my disks at home). But both hd-partitions are not touched by any program variables, so I had only once a virus hiding on them (I hardly ever check all my partitions - maybe once in a month) - most malicious stuff writes itself to your C: drive where all the programs are (plus in my case to the I: partion which is my last one and set aside only for memory cache and IE/mozilla caches) - they are the ones I check daily.

Older content and pages I move usually onto a different partion and back-up from there onto CDs.
I don't play games so modern HDs are far too large for my needs.
Only new content gets burned asap because I don't want to risk loosing it.