Albert Hoffman, RIP

[SheepGuy]

Just got this in the mail, a flashback

Apr 29, 10:44 PM (ET)

NEW YORK (AP) - Albert Hofmann, the father of the mind-altering drug LSD
whose medical discovery grew into a notorious "problem child," died Tuesday.
He was 102.

Hofmann died of a heart attack at his home in Basel, Switzerland, according
to Rick Doblin, president of the Multidisciplinary Association for
Psychedelic Studies, in a statement posted on the association's Web site.

Hofmann's hallucinogen inspired - and arguably corrupted - millions in the
1960's hippy generation. For decades after LSD was banned in the late 1960s,
Hofmann defended his invention.

"I produced the substance as a medicine ... It's not my fault if people
abused it," he once said.


The Swiss chemist discovered lysergic acid diethylamide-25 in 1938 while
studying the medicinal uses of a fungus found on wheat and other grains at
the Sandoz pharmaceuticals firm in Basel.

He became the first human guinea pig of the drug when a tiny amount of the
substance seeped on to his finger during a repeat of the laboratory
experiment April 16, 1943.

"I had to leave work for home because I was suddenly hit by a sudden feeling
of unease and mild dizziness," he subsequently wrote in a memo to company
bosses.

"Everything I saw was distorted as in a warped mirror," he said, describing
his bicycle ride home. "I had the impression I was rooted to the spot. But
my assistant told me we were actually going very fast."

Three days later, Hofmann experimented with a larger dose. The result was a
horror trip.

"The substance which I wanted to experiment with took over me. I was filled
with an overwhelming fear that I would go crazy. I was transported to a
different world, a different time," Hofmann wrote.

There was no answer at Hofmann's home on Tuesday and a person who answered
the phone at Novartis, a former employer, said the company had no knowledge
of his death.

Hofmann and his scientific colleagues hoped that LSD would make an important
contribution to psychiatric research. The drug exaggerated inner problems
and conflicts and thus it was hoped that it might be used to recognize and
treat mental illness like schizophrenia.

For a time, Sandoz sold LSD 25 under the name Delysid, encouraging doctors
to try it themselves. It was one of the strongest drugs in medicine - with
just one gram enough to drug an estimated 10,000 to 20,000 people for 12
hours.

Hofmann discovered the drug had a similar chemical structure to psychedelic
mushrooms and herbs used in religious ceremonies by Mexican Indians.

LSD was elevated to international fame in the late 1950s and 1960s thanks to
Harvard professor Timothy Leary who embraced the drug under the slogan "turn
on, tune in, drop out." The film star Cary Grant and numerous rock musicians
extolled its virtues in achieving true self discovery and enlightenment.

But away from the psychedelic trips and flower children, horror stories
emerged about people going on murder sprees or jumping out of windows while
hallucinating. Heavy users suffered permanent psychological damage.

The U.S. government banned LSD in 1966 and other countries followed suit.

Hofmann maintained this was unfair, arguing that the drug was not addictive.
He repeatedly maintained the ban should be lifted to allow LSD to be used in
medical research.

He himself took the drug - purportedly on an occasional basis and out of
scientific interest - for several decades.

"LSD can help open your eyes," he once said. "But there are other ways -
meditation, dance, music, fasting."

Even so, the self described "father" of LSD readily agreed that the drug was
dangerous if in the wrong hands. This was reflected by the title of his 1979
book: "LSD - my problem child."

Hofmann retired from Sandoz in 1971. He devoted his time to travel, writing
and lectures - which often reflected his growing interest with philosophy
and religious questions.

He lived in a small picturesque village in the Swiss Jura mountains and
remained active until his early 90's.