Work with many or fewer sponsors?

[tickler]

For me personally, I find letting the surfer choose which site they like best, converts best, and controls how much I promote a sponsors site.

So build a list for Teens, Asians, MILFs, whatever.
Put a HPA for your best converting at the top, a banner for your second best underneath, and text links for the rest. Check your ratios and move the better ones up and the worst ones down.